Philadelphia’s Vivodyne, an AI-powered biotech firm, recently secured a substantial $38 million in seed funding led by Khosla Ventures, joined by CS Ventures, Kairos Ventures, Bison Ventures, and MBX Capital. Specializing in drug discovery, Vivodyne harnesses predictive AI to pinpoint therapeutic targets and forecast individual drug responses using lab-grown human organ tissues. Their robotic technology facilitates testing on over 10,000 tissues concurrently, generating extensive datasets for AI training. This funding boost will propel their drug-discovery pipeline and enhance their AI infrastructure. Khosla Ventures’ Alex Morgan praised Vivodyne’s ability to advance therapeutic success rates by automating testing procedures on realistic human tissues, a significant leap for the pharmaceutical industry. In the rapidly evolving realm of AI-driven drug discovery, companies like Genesis and AION Labs are making strides, with Genesis securing $200 million in funding and AION Labs introducing DenovAI, an AI-powered platform for antibody discovery, backed by major pharma and tech players like AstraZeneca, Merck, and Amazon Web Services.
Philadelphia-based AI-enabled biotech company Vivodyne announced it closed a $38 million seed funding round led by Khosla Ventures.
CS Ventures, Kairos Ventures, Bison Ventures, and MBX Capital also participated in the round.
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Vivodyne is a drug discovery company that uses clinically predictive AI to help identify therapeutic targets and predict a patient’s response to a drug by testing it on lab-grown human organ tissues.
Utilizing robotic automation, the company can dose, cultivate, and analyze more than 10,000 individual tissues at a time, creating a vast number of human datasets for AI training.
The company will use the funds to advance its drug-discovery pipeline, as well as its AI stack.
“By testing drugs and life-saving biologics directly on these realistic human tissues at an unprecedented scale and resolution, we can improve the success rates of therapeutics entering clinical trials,” Alex Morgan, partner at Khosla Ventures, said in a statement.
“Vivodyne’s technology bridges the gap between preclinical R&D and human clinical trials while automating every step of the testing pipeline, from growing tissues, dosing, sampling, and imaging, to analyzing data. The ability to screen and develop new potential life-saving therapies, testing thousands at a time on functionally realistic human tissues on Vivodyne’s automated platform, is a major step forward for the pharmaceutical industry.”
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Open-source databases and AI-based software are increasingly used to aid in drug discovery. Still, experts say “mind and machine need to work in synergy,” with collaboration occurring across multiple disciplines, including academia and industry.
Numerous companies are utilizing AI for drug discovery, including California-based AI drug discovery startup Genesis, which devised its molecular AI platform Genesis Exploration of Molecular Space (GEMS) that merges deep learning and molecular simulations to create high-potency small-molecule drugs.
In August, Genesis scored $200 million in an oversubscribed Series B funding round, bringing its total raise to $280 million.
Israel-based AION Labs, an AI-enabled drug-discovery partnership between global pharma and tech companies, announced the launch of its second startup, DenovAI, in February.
DenovAI is an AI-enabled computational biophysics platform that can discover potential antibodies aimed at specific epitopes (the part of an antigen molecule recognized by the immune system to which an antibody attaches itself). The company said its platform will design antibodies from scratch and suggest which candidates will likely make effective drugs.
AION Labs includes pharma giants AstraZeneca, Merck, Pfizer, and Teva, alongside venture capital firm Israel Biotech Fund, strategic partner Amazon Web Services, and German independent research institute Bio Med X.
Source: MobiHealthnews