Conduit Pharmaceuticals (Nasdaq: CDT) has teamed up with ClinConnect, a pioneering patient-clinical trial matchmaking platform, to initiate a cocrystal development program for evaluating Conduit’s AZD1656 compound. AZD1656 shows promise in treating autoimmune disorders, and the cocrystal program aims to enhance its solubility, stability, and bioavailability. By partnering with ClinConnect, Conduit seeks to expedite the compound’s development and offer a more efficient pathway for patients. Conduit’s unique approach involves acquiring assets post pre-clinical and clinical testing and accelerating them through Phase II trials, with potential third-party license deals upon success.
Conduit Pharmaceuticals Inc. (Nasdaq: CDT) (“Conduit Pharmaceuticals” or “Conduit”), a multi-asset clinical-stage disease-agnostic life science company providing an efficient model for compound development, today announced a partnership with ClinConnect, a first-of-its-kind platform redefining how patients and clinical trials find each other, to conduct a cocrystal development program to evaluate Conduit’s AZD1656 compound.
AZD1656 is a molecule with potential treatment applications currently in a wide variety of autoimmune disorders. The cocrystal program will seek to identify, characterize, and validate suitable cocrystal partners for AZD1656 to solve for current challenges associated with solubility, stability, and bioavailability. Pharmaceutical cocrystals may improve vital physicochemical characteristics of a drug, including solubility, dissolution, bioavailability, and stability of pharmaceutical compounds, while maintaining its therapeutic activity.
“Working with ClinConnect to develop this cocrystal program and advance AZD1656 was a natural fit. Together, we hope to move this compound forward faster than through traditional channels and with the same scientific rigor,” said Dr. David Tapolczay, Chief Executive Officer of Conduit. “AZD1656 has shown promise in early studies already conducted by AstraZeneca, and we are thrilled at its potential. We’re proud to act swiftly in pursuit of our goal of offering a leaner, more efficient, and effective pathway to advance compelling assets for patients.”
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Conduit Pharmaceuticals departs from the traditional business model of shepherding assets through an entire commercial lifecycle. Instead, Conduit, which went public on the Nasdaq in September 2023, acquires assets that have already undergone some pre-clinical and clinical testing, working to accelerate them through Phase II trials and, if successful through Phase II trials, intends to seek exits through third-party license deals.
“This partnership is a significant milestone for ClinConnect and is directly in line with our mission to build the bridge between patients and the treatments they deserve access to,” said Robert Maxwell, Founder and Chief Executive Officer at ClinConnect. “Conduit’s model is particularly inspiring for us, as it works creatively to help ensure that assets that can save patient lives will not sit on the shelf. Through our work together, we hope to accelerate potential care for patients who could benefit from this molecule and others, potentially enabling access to life-saving innovations earlier.”
Source: Biospace
