MedPharm, the leader in cannabis research and formulation development, which has agreed to be acquired by Medicine Man Technologies (OTCQX: MDCL), will launch a landmark, double-blind, placebo controlled clinical trial in the first half of 2020 to explore how cannabis works for patients with Dementia and Alzheimer’s.
Medicine Man Technologies Acquisiton Target, MedPharm, to Launch a Landmark Randomized Clinical Trial Taking Aim at Treating Alzheimer’s with Cannabis
MedPharm will be exploring the action of a research-based, scientifically formulated compound containing cannabinoids and nootropic nutrients in patients diagnosed with Dementia and Alzheimer’s. The study will encompass patient surveys, memory tests, caregiver surveys, brain scans, and blood tests.
“MedPharm will investigate a proprietary compound that contains naturally derived cannabinoids and excipients that have been scientifically demonstrated to positively affect brain function, with the goal of helping us better understand and treat Alzheimer’s,” Dr. Tyrell Towle, MedPharm research scientist, says.
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“This study is the first of its kind and demonstrates that research teams like ours continue to investigate more and more details about the amazing properties of the cannabis plant and the actions of its various compounds working with the human endocannabinoid system,” Albert Gutierrez, CEO of MedPharm, says. “We intend to discover applications that successfully treat symptoms of complicated and incurable human diseases that have confounded traditional medical science.”
Researchers from around the world have investigated the effects of THC in vitro on cellular systems known to be involved in Alzheimer’s and Dementia. To date, the majority of cannabis research has been observational.
However, under Colorado’s research license, MedPharm is able to prepare placebo and active medications for distribution to study patients.
MedPharm’s research partners include a world-renowned neurologist; CereScan®, a functional brain imaging and analytics company; and a cutting-edge blood testing company that will evaluate the levels of neuroinflammatory biomarkers.
The team will evaluate and compare the effect of the formulation in over 120 regions of the brain and analyze the results against a large database of brain scans. “At CereScan®, we are proud to play a part in helping our clients assess the safety and efficacy, through advanced biomarkers, of new treatments that improve people’s lives,” said John Kelley, President and CEO of CereScan®.
Alzheimer’s disease (AD) is an incurable, chronic debilitating neuro-degenerative condition that is associated with progressive cognitive decline and profound neuronal loss. It is estimated to affect 10 percent of people over the age of 65 years, and 25 percent of people over the age of 80 years.
The United Nations population projections estimate that 370 million people will be older than 80 years by 2050 and the associated increase in patients with AD will pose a substantial socio-economic burden.
Source: Yahoo