IRX Therapeutics, Inc. today announced that the company’s assets have been acquired by the newly formed Brooklyn ImmunoTherapeutics LLC. This name reflects the company’s focus on advancing the science of cytokine-based immunotherapy for the treatment of a range of cancers.
“Cytokine-based immunotherapy overcomes immune suppression to activate an immune attack on tumors by upregulating multiple checkpoints and represents an exciting new approach to treating cancer,” said Charles Cherington, General Partner and Board Chair of Brooklyn ImmunoTherapeutics. “In a Phase 2A clinical trial, IRX-2, our clinical drug candidate, demonstrated an improvement in progression free survival and overall survival in patients with head and neck squamous cell carcinoma. We believe this unique injectable cytokine mixture amplified from normal donor lymphocytes has the potential to improve patient outcomes both as a single agent and in combination with other anti-cancer agents. We are committed to exploring this potential in a range of solid tumors including breast cancer, cervical and vulvar neoplasms, renal cell carcinoma, hepatocellular carcinoma, gastric and esophageal cancer as well as other solid tumor indications.”
A global, multicenter, randomized, double-blind, placebo-controlled Phase 2B clinical trial of IRX-2 in 105 patients with head and neck squamous cell carcinoma has completed enrollment with results expected in mid-2020.
Date: November 12, 2018
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Source: BusinessWire
